Life and death as a T lymphocyte: from immune protection to HIV pathogenesis

Detailed analysis of T cell dynamics in humans is challenging and mouse models can be important tools for characterizing T cell dynamic processes. In a paper just published in Journal of Biology, Marques et al. suggest that a mouse model with its activated CD4(+ )T cells are deleted has relevance fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Vrisekoop, Nienke, Mandl, Judith N, Germain, Ronald N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790836/
https://www.ncbi.nlm.nih.gov/pubmed/19951397
http://dx.doi.org/10.1186/jbiol198
Descripción
Sumario:Detailed analysis of T cell dynamics in humans is challenging and mouse models can be important tools for characterizing T cell dynamic processes. In a paper just published in Journal of Biology, Marques et al. suggest that a mouse model with its activated CD4(+ )T cells are deleted has relevance for HIV infection. See research article http://jbiol.com/content/8/10/93

Ejemplares similares