Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-β signaling and metastasis

INTRODUCTION: Mammary tumorigenesis is associated with the increased expression of several proteins in the focal adhesion complex, including focal adhesion kinase (FAK) and various integrins. Aberrant expression of these molecules occurs concomitant with the conversion of TGF-β function from a tumor...

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Detalles Bibliográficos
Autores principales: Wendt, Michael K, Schiemann, William P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790843/
https://www.ncbi.nlm.nih.gov/pubmed/19740433
http://dx.doi.org/10.1186/bcr2360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790843/
https://www.ncbi.nlm.nih.gov/pubmed/19740433
http://dx.doi.org/10.1186/bcr2360

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