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Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-β signaling and metastasis
INTRODUCTION: Mammary tumorigenesis is associated with the increased expression of several proteins in the focal adhesion complex, including focal adhesion kinase (FAK) and various integrins. Aberrant expression of these molecules occurs concomitant with the conversion of TGF-β function from a tumor...
Autores principales: | Wendt, Michael K, Schiemann, William P |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790843/ https://www.ncbi.nlm.nih.gov/pubmed/19740433 http://dx.doi.org/10.1186/bcr2360 |
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