Evolutionarily conserved proteins MnmE and GidA catalyze the formation of two methyluridine derivatives at tRNA wobble positions

The wobble uridine of certain bacterial and mitochondrial tRNAs is modified, at position 5, through an unknown reaction pathway that utilizes the evolutionarily conserved MnmE and GidA proteins. The resulting modification (a methyluridine derivative) plays a critical role in decoding NNG/A codons an...

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Detalles Bibliográficos
Autores principales: Moukadiri, Ismaïl, Prado, Silvia, Piera, Julio, Velázquez-Campoy, Adrián, Björk, Glenn R., Armengod, M.-Eugenia
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790889/
https://www.ncbi.nlm.nih.gov/pubmed/19767610
http://dx.doi.org/10.1093/nar/gkp762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790889/
https://www.ncbi.nlm.nih.gov/pubmed/19767610
http://dx.doi.org/10.1093/nar/gkp762

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