Cargando…
Evolutionarily conserved proteins MnmE and GidA catalyze the formation of two methyluridine derivatives at tRNA wobble positions
The wobble uridine of certain bacterial and mitochondrial tRNAs is modified, at position 5, through an unknown reaction pathway that utilizes the evolutionarily conserved MnmE and GidA proteins. The resulting modification (a methyluridine derivative) plays a critical role in decoding NNG/A codons an...
Autores principales: | Moukadiri, Ismaïl, Prado, Silvia, Piera, Julio, Velázquez-Campoy, Adrián, Björk, Glenn R., Armengod, M.-Eugenia |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790889/ https://www.ncbi.nlm.nih.gov/pubmed/19767610 http://dx.doi.org/10.1093/nar/gkp762 |
Ejemplares similares
-
Further insights into the tRNA modification process controlled by proteins MnmE and GidA of Escherichia coli
por: Yim, Lucía, et al.
Publicado: (2006) -
The output of the tRNA modification pathways controlled by the Escherichia coli MnmEG and MnmC enzymes depends on the growth conditions and the tRNA species
por: Moukadiri, Ismaïl, et al.
Publicado: (2014) -
The tRNA-modifying function of MnmE is controlled by post-hydrolysis steps of its GTPase cycle
por: Prado, Silvia, et al.
Publicado: (2013) -
tRNA Modification Enzymes GidA and MnmE: Potential Role in Virulence of Bacterial Pathogens
por: Shippy, Daniel C., et al.
Publicado: (2014) -
Proteomic and Metabolomic Analyses Provide Insights into the Mechanism on Arginine Metabolism Regulated by tRNA Modification Enzymes GidA and MnmE of Streptococcus suis
por: Gao, Ting, et al.
Publicado: (2020)