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Functional Expression of the Na-K-2Cl Cotransporter NKCC2 in Mammalian Cells Fails to Confirm the Dominant-negative Effect of the AF Splice Variant

The renal bumetanide-sensitive Na-K-2Cl cotransporter (NKCC2) is the major salt transport pathway in the apical membrane of the mammalian thick ascending limb. It is differentially spliced and the three major variants (A, B, and F) differ in their localization and transport characteristics. Most kno...

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Detalles Bibliográficos
Autores principales:	Hannemann, Anke, Christie, Jenny K., Flatman, Peter W.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2009
Materias:	Membrane Transport, Structure, Function, and Biogenesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790964/ https://www.ncbi.nlm.nih.gov/pubmed/19854835 http://dx.doi.org/10.1074/jbc.M109.060004

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