Trichostatin A enhances proliferation and migration of vascular smooth muscle cells by downregulating thioredoxin 1

AIMS: A reduction in the level of thioredoxin 1 (Trx1) has been proposed as a possible mechanism for the tumor-specific growth arrest caused by inhibition of histone deacetylases (HDACs). In this study, we investigated the effect of trichostatin A (TSA), a potent HDAC inhibitor, on the proliferation...

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Detalles Bibliográficos
Autores principales: Song, Seungjeong, Kang, Sang Won, Choi, Chulhee
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791053/
https://www.ncbi.nlm.nih.gov/pubmed/19633316
http://dx.doi.org/10.1093/cvr/cvp263

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