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TGF-β and IL-10 Production by HIV-Specific CD8+ T Cells Is Regulated by CTLA-4 Signaling on CD4+ T Cells

Immune dysregulation in HIV-1 infection is associated with increased expression of inhibitory molecules such as CTLA-4, TGF-β, and IL-10. In this study we examined one potential mechanism for regulating TGF-β and IL-10 expression by HIV-specific suppressor CD8+ T cells. No overlap between TGF-β, IL-...

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Detalles Bibliográficos
Autores principales:	Elrefaei, Mohamed, Burke, Candace M., Baker, Chris A. R., Jones, Norman G., Bousheri, Stephanie, Bangsberg, David R., Cao, Huyen
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791208/ https://www.ncbi.nlm.nih.gov/pubmed/20016783 http://dx.doi.org/10.1371/journal.pone.0008194

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