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An MHC-I Cytoplasmic Domain/HIV-1 Nef Fusion Protein Binds Directly to the μ Subunit of the AP-1 Endosomal Coat Complex

BACKGROUND: The down-regulation of the major histocompatibility complex class I (MHC-I) from the surface of infected cells by the Nef proteins of primate immunodeficiency viruses likely contributes to pathogenesis by providing evasion of cell-mediated immunity. HIV-1 Nef-induced down-regulation invo...

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Detalles Bibliográficos
Autores principales:	Singh, Rajendra Kumar, Lau, David, Noviello, Colleen M., Ghosh, Partho, Guatelli, John C.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791223/ https://www.ncbi.nlm.nih.gov/pubmed/20020046 http://dx.doi.org/10.1371/journal.pone.0008364

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