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A Strategy for Adenovirus Vector Targeting with a Secreted Single Chain Antibody
BACKGROUND: Successful gene therapy will require targeted delivery vectors capable of self-directed localization. In this regard, the use of antibodies or single chain antibody fragments (scFv) in conjunction with adenovirus (Ad) vectors remains an attractive means to achieve cell-specific targeting...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791226/ https://www.ncbi.nlm.nih.gov/pubmed/20027223 http://dx.doi.org/10.1371/journal.pone.0008355 |