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A Biochemical Genomics Screen for Substrates of Ste20p Kinase Enables the In Silico Prediction of Novel Substrates
The Ste20/PAK family is involved in many cellular processes, including the regulation of actin-based cytoskeletal dynamics and the activation of MAPK signaling pathways. Despite its numerous roles, few of its substrates have been identified. To better characterize the roles of the yeast Ste20p kinas...
Autores principales: | Annan, Robert B., Lee, Anna Y., Reid, Ian D., Sayad, Azin, Whiteway, Malcolm, Hallett, Michael, Thomas, David Y. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791418/ https://www.ncbi.nlm.nih.gov/pubmed/20020052 http://dx.doi.org/10.1371/journal.pone.0008279 |
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