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Identification of Human GnIH Homologs, RFRP-1 and RFRP-3, and the Cognate Receptor, GPR147 in the Human Hypothalamic Pituitary Axis

The existence of a hypothalamic gonadotropin-inhibiting system has been elusive. A neuropeptide named gonadotropin-inhibitory hormone (GnIH, SIKPSAYLPLRF-NH(2)) which directly inhibits gonadotropin synthesis and release from the pituitary was recently identified in quail hypothalamus. Here we identi...

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Detalles Bibliográficos
Autores principales:	Ubuka, Takayoshi, Morgan, Kevin, Pawson, Adam J., Osugi, Tomohiro, Chowdhury, Vishwajit S., Minakata, Hiroyuki, Tsutsui, Kazuyoshi, Millar, Robert P., Bentley, George E.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791420/ https://www.ncbi.nlm.nih.gov/pubmed/20027225 http://dx.doi.org/10.1371/journal.pone.0008400

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