A Novel Phase Variation Mechanism in the Meningococcus Driven by a Ligand-Responsive Repressor and Differential Spacing of Distal Promoter Elements

Phase variable expression, mediated by high frequency reversible changes in the length of simple sequence repeats, facilitates adaptation of bacterial populations to changing environments and is frequently important in bacterial virulence. Here we elucidate a novel phase variable mechanism for NadA,...

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Detalles Bibliográficos
Autores principales: Metruccio, Matteo M. E., Pigozzi, Eva, Roncarati, Davide, Berlanda Scorza, Francesco, Norais, Nathalie, Hill, Stuart A., Scarlato, Vincenzo, Delany, Isabel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791445/
https://www.ncbi.nlm.nih.gov/pubmed/20041170
http://dx.doi.org/10.1371/journal.ppat.1000710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791445/
https://www.ncbi.nlm.nih.gov/pubmed/20041170
http://dx.doi.org/10.1371/journal.ppat.1000710

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