SH2 domains: modulators of nonreceptor tyrosine kinase activity

The Src homology 2 (SH2) domain is a sequence-specific phosphotyrosine-binding module present in many signaling molecules. In cytoplasmic tyrosine kinases, the SH2 domain is located N-terminally to the catalytic kinase domain (SH1) where it mediates cellular localization, substrate recruitment, and...

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Detalles Bibliográficos
Autores principales: Filippakopoulos, Panagis, Müller, Susanne, Knapp, Stefan
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791838/
https://www.ncbi.nlm.nih.gov/pubmed/19926274
http://dx.doi.org/10.1016/j.sbi.2009.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791838/
https://www.ncbi.nlm.nih.gov/pubmed/19926274
http://dx.doi.org/10.1016/j.sbi.2009.10.001

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