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Impaired Terminal Differentiation of Hippocampal Granule Neurons and Defective Contextual Memory in PC3/Tis21 Knockout Mice

Neurogenesis in the dentate gyrus of the adult hippocampus has been implicated in neural plasticity and memory, but the molecular mechanisms controlling the proliferation and differentiation of newborn neurons and their integration into the synaptic circuitry are still largely unknown. To investigat...

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Detalles Bibliográficos
Autores principales: Farioli-Vecchioli, Stefano, Saraulli, Daniele, Costanzi, Marco, Leonardi, Luca, Cinà, Irene, Micheli, Laura, Nutini, Michele, Longone, Patrizia, Oh, S. Paul, Cestari, Vincenzo, Tirone, Felice
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791842/
https://www.ncbi.nlm.nih.gov/pubmed/20020054
http://dx.doi.org/10.1371/journal.pone.0008339