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PECAM-1 expression and activity negatively regulate multiple platelet signaling pathways

Platelet endothelial cell adhesion molecule-1 (PECAM-1) inhibits platelet response to collagen and may also inhibit two other major platelet agonists ADP and thrombin although this has been less well explored. We hypothesized that the combined effect of inhibiting these three platelet activating pat...

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Detalles Bibliográficos
Autores principales:	Jones, Chris I., Garner, Stephen F., Moraes, Leonardo A., Kaiser, William J., Rankin, Angela, Ouwehand, Willem H., Goodall, Alison H., Gibbins, Jonathan M.
Formato:	Texto
Lenguaje:	English
Publicado:	Elsevier Science B.V 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791847/ https://www.ncbi.nlm.nih.gov/pubmed/19850043 http://dx.doi.org/10.1016/j.febslet.2009.10.037

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