Aminoglycoside resistance genes sgm and kgmB protect bacterial but not yeast small ribosomal subunits in vitro despite high conservation of the rRNA A-site

The aminoglycoside resistance genes sgm from Micromonospora zionensis and kgmB from Streptomyces tenebrarius were cloned into a yeast expression vector to test whether the encoded prokaryotic methylases can modify the 18S rRNA A-site and thus confer resistance to G-418. Despite the detectable presen...

Descripción completa

Detalles Bibliográficos
Autores principales: Tomic, Tatjana Ilic, Moric, Ivana, Conn, Graeme L., Vasiljevic, Branka
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791848/
https://www.ncbi.nlm.nih.gov/pubmed/18930134
http://dx.doi.org/10.1016/j.resmic.2008.09.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791848/
https://www.ncbi.nlm.nih.gov/pubmed/18930134
http://dx.doi.org/10.1016/j.resmic.2008.09.006

Ejemplares similares