Structural Characterisation of Ligand-Binding Determinants in Human Lung Surfactant Protein D: Influence of Asp325

The crystal structures of a biologically and therapeutically active recombinant homotrimeric fragment of human lung surfactant protein D with a series of bound ligands have been determined. While the structures reveal various different binding modes, all utilise a similarly positioned pair of mannos...

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Detalles Bibliográficos
Autores principales: Shrive, A.K., Martin, C., Burns, I., Paterson, J.M., Martin, J.D., Townsend, J.P., Waters, P., Clark, H.W., Kishore, U., Reid, K.B.M., Greenhough, T.J.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791854/
https://www.ncbi.nlm.nih.gov/pubmed/19799916
http://dx.doi.org/10.1016/j.jmb.2009.09.057

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