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Mechanisms and functional implications of the degradation of host RNA polymerase II in influenza virus infected cells
Influenza viruses induce a host shut off mechanism leading to the general inhibition of host gene expression in infected cells. Here, we report that the large subunit of host RNA polymerase II (Pol II) is degraded in infected cells and propose that this degradation is mediated by the viral RNA polym...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791857/ https://www.ncbi.nlm.nih.gov/pubmed/19875144 http://dx.doi.org/10.1016/j.virol.2009.10.003 |