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A Protocadherin-Cadherin-FLRT3 Complex Controls Cell Adhesion and Morphogenesis

BACKGROUND: Paraxial protocadherin (PAPC) and fibronectin leucine-rich domain transmembrane protein-3 (FLRT3) are induced by TGFβ signaling in Xenopus embryos and both regulate morphogenesis by inhibiting C-cadherin mediated cell adhesion. PRINCIPAL FINDINGS: We have investigated the functional and...

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Detalles Bibliográficos
Autores principales: Chen, Xuejun, Koh, Eunjin, Yoder, Michael, Gumbiner, Barry M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791867/
https://www.ncbi.nlm.nih.gov/pubmed/20027292
http://dx.doi.org/10.1371/journal.pone.0008411