High Performance Thin Layer Chromatographic Method for Simultaneous Estimation of Ibuprofen and Pseudoephedrine Hydrochloride

High performance thin layer chromatographic method is developed for simultaneous estimation of ibuprofen and pseudoephedrine hydrochloride in tablets. Silica gel 60F(254) plates were used as stationary phase and t.butanol: ethyl acetate: glacial acetic acid: water (7:4:2:2 v/v) as mobile phase. Wave...

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Autores principales: Chitlange, S. S., Sakarkar, D. M., Wankhede, S. B., Wadodkar, S. G.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2008
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792507/
https://www.ncbi.nlm.nih.gov/pubmed/20046759
http://dx.doi.org/10.4103/0250-474X.43018
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author Chitlange, S. S.
Sakarkar, D. M.
Wankhede, S. B.
Wadodkar, S. G.
author_facet Chitlange, S. S.
Sakarkar, D. M.
Wankhede, S. B.
Wadodkar, S. G.
author_sort Chitlange, S. S.
collection PubMed
description High performance thin layer chromatographic method is developed for simultaneous estimation of ibuprofen and pseudoephedrine hydrochloride in tablets. Silica gel 60F(254) plates were used as stationary phase and t.butanol: ethyl acetate: glacial acetic acid: water (7:4:2:2 v/v) as mobile phase. Wavelength selected for analysis was 254 nm. Percent estimation of ibuprofen and pseudoephedrine hydrochloride was found to be 99.56% and 98.77%, respectively. Percent recovery for both the drugs was found in the range of 98.27% to 100.91%, respectively.
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spelling pubmed-27925072009-12-14 High Performance Thin Layer Chromatographic Method for Simultaneous Estimation of Ibuprofen and Pseudoephedrine Hydrochloride Chitlange, S. S. Sakarkar, D. M. Wankhede, S. B. Wadodkar, S. G. Indian J Pharm Sci Short Communications High performance thin layer chromatographic method is developed for simultaneous estimation of ibuprofen and pseudoephedrine hydrochloride in tablets. Silica gel 60F(254) plates were used as stationary phase and t.butanol: ethyl acetate: glacial acetic acid: water (7:4:2:2 v/v) as mobile phase. Wavelength selected for analysis was 254 nm. Percent estimation of ibuprofen and pseudoephedrine hydrochloride was found to be 99.56% and 98.77%, respectively. Percent recovery for both the drugs was found in the range of 98.27% to 100.91%, respectively. Medknow Publications 2008 /pmc/articles/PMC2792507/ /pubmed/20046759 http://dx.doi.org/10.4103/0250-474X.43018 Text en © Indian Journal of Pharmaceutical Sciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communications
Chitlange, S. S.
Sakarkar, D. M.
Wankhede, S. B.
Wadodkar, S. G.
High Performance Thin Layer Chromatographic Method for Simultaneous Estimation of Ibuprofen and Pseudoephedrine Hydrochloride
title High Performance Thin Layer Chromatographic Method for Simultaneous Estimation of Ibuprofen and Pseudoephedrine Hydrochloride
title_full High Performance Thin Layer Chromatographic Method for Simultaneous Estimation of Ibuprofen and Pseudoephedrine Hydrochloride
title_fullStr High Performance Thin Layer Chromatographic Method for Simultaneous Estimation of Ibuprofen and Pseudoephedrine Hydrochloride
title_full_unstemmed High Performance Thin Layer Chromatographic Method for Simultaneous Estimation of Ibuprofen and Pseudoephedrine Hydrochloride
title_short High Performance Thin Layer Chromatographic Method for Simultaneous Estimation of Ibuprofen and Pseudoephedrine Hydrochloride
title_sort high performance thin layer chromatographic method for simultaneous estimation of ibuprofen and pseudoephedrine hydrochloride
topic Short Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792507/
https://www.ncbi.nlm.nih.gov/pubmed/20046759
http://dx.doi.org/10.4103/0250-474X.43018
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