Modeling of Environmental Effects in Genome-Wide Association Studies Identifies SLC2A2 and HP as Novel Loci Influencing Serum Cholesterol Levels

Genome-wide association studies (GWAS) have identified 38 larger genetic regions affecting classical blood lipid levels without adjusting for important environmental influences. We modeled diet and physical activity in a GWAS in order to identify novel loci affecting total cholesterol, LDL cholester...

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Detalles Bibliográficos
Autores principales: Igl, Wilmar, Johansson, Åsa, Wilson, James F., Wild, Sarah H., Polašek, Ozren, Hayward, Caroline, Vitart, Veronique, Hastie, Nicholas, Rudan, Pavao, Gnewuch, Carsten, Schmitz, Gerd, Meitinger, Thomas, Pramstaller, Peter P., Hicks, Andrew A., Oostra, Ben A., van Duijn, Cornelia M., Rudan, Igor, Wright, Alan, Campbell, Harry, Gyllensten, Ulf
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792712/
https://www.ncbi.nlm.nih.gov/pubmed/20066028
http://dx.doi.org/10.1371/journal.pgen.1000798

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