The Constitutively Active V2 Receptor Mutants Conferring NSIAD Are Weakly Sensitive to Agonist and Antagonist Regulation

Patients having the nephrogenic syndrome of inappropriate antidiuresis present either the R137C or R137L V2 mutated receptor. While the clinical features have been characterized, the molecular mechanisms of functioning of these two mutants remain elusive. In the present study, we compare the pharmac...

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Detalles Bibliográficos
Autores principales: Tenenbaum, Julie, Ayoub, Mohammed A., Perkovska, Sanja, Adra-Delenne, Anne-Laure, Mendre, Christiane, Ranchin, Bruno, Bricca, Giamperro, Geelen, Ghislaine, Mouillac, Bernard, Durroux, Thierry, Morin, Denis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792721/
https://www.ncbi.nlm.nih.gov/pubmed/20027297
http://dx.doi.org/10.1371/journal.pone.0008383

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