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Detection of GAD65 Autoreactive T-Cells by HLA Class I Tetramers in Type 1 Diabetic Patients

Type 1 diabetes (T1D) is an autoimmune disease, in which pancreatic β cells are destroyed in genetically predisposed individuals. While the direct contribution of autoantibodies to the disease pathogenesis is controversial, it is generally recognised that the mechanism of β cell destruction is media...

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Detalles Bibliográficos
Autores principales: Giuliani, Laura, Mele, Raffaella, Di Giovine, Monica, Altieri, Laura, Crinò, Antonino, Ravà, Lucilla, Fierabracci, Alessandra
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792951/
https://www.ncbi.nlm.nih.gov/pubmed/20029631
http://dx.doi.org/10.1155/2009/576219

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