Molecular Basis of Recognition of Human Osteopontin by 23C3, a Potential Therapeutic Antibody for Treatment of Rheumatoid Arthritis

Osteopontin plays an important role in the development and perpetuation of rheumatoid arthritis (RA). Antibodies targeting osteopontin have shown promising therapeutic benefits against this disease. We have previously reported a novel anti-RA monoclonal antibody, namely, 23C3, and shown it capable o...

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Detalles Bibliográficos
Autores principales: Du, Jiamu, Hou, Sheng, Zhong, Chen, Lai, Zheng, Yang, Hui, Dai, Jianxin, Zhang, Dapeng, Wang, Hao, Guo, Yajun, Ding, Jianping
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2008
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793339/
https://www.ncbi.nlm.nih.gov/pubmed/18694758
http://dx.doi.org/10.1016/j.jmb.2008.07.075

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