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Disentangling Direct from Indirect Co-Evolution of Residues in Protein Alignments
Predicting protein structure from primary sequence is one of the ultimate challenges in computational biology. Given the large amount of available sequence data, the analysis of co-evolution, i.e., statistical dependency, between columns in multiple alignments of protein domain sequences remains one...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793430/ https://www.ncbi.nlm.nih.gov/pubmed/20052271 http://dx.doi.org/10.1371/journal.pcbi.1000633 |