Solid polymeric microparticles enhance the delivery of siRNA to macrophages in vivo

Therapeutics based on small interfering RNA (siRNA) have a great clinical potential; however, delivery problems have limited their clinical efficacy, and new siRNA delivery vehicles are greatly needed. In this report, we demonstrate that submicron particles (800–900 nm) composed of the polyketal PK3...

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Detalles Bibliográficos
Autores principales: Lee, Sungmun, Yang, Stephen C., Kao, Chen-Yu, Pierce, Robert H., Murthy, Niren
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794160/
https://www.ncbi.nlm.nih.gov/pubmed/19783825
http://dx.doi.org/10.1093/nar/gkp758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794160/
https://www.ncbi.nlm.nih.gov/pubmed/19783825
http://dx.doi.org/10.1093/nar/gkp758

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