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Local false discovery rate facilitates comparison of different microarray experiments

The local false discovery rate (LFDR) estimates the probability of falsely identifying specific genes with changes in expression. In computer simulations, LFDR <10% successfully identified genes with changes in expression, while LFDR >90% identified genes without changes. We used LFDR to compa...

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Detalles Bibliográficos
Autores principales: Hong, Wan-Jen, Tibshirani, Robert, Chu, Gilbert
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794175/
https://www.ncbi.nlm.nih.gov/pubmed/19825981
http://dx.doi.org/10.1093/nar/gkp813