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Nucleotide modifications in three functionally important regions of the Saccharomyces cerevisiae ribosome affect translation accuracy

Important regions of rRNA are rich in nucleotide modifications that can have strong effects on ribosome biogenesis and translation efficiency. Here, we examine the influence of pseudouridylation and 2′-O-methylation on translation accuracy in yeast, by deleting the corresponding guide snoRNAs. The r...

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Detalles Bibliográficos
Autores principales: Baudin-Baillieu, Agnès, Fabret, Céline, Liang, Xue-hai, Piekna-Przybylska, Dorota, Fournier, Maurille J., Rousset, Jean-Pierre
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794176/
https://www.ncbi.nlm.nih.gov/pubmed/19820108
http://dx.doi.org/10.1093/nar/gkp816