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Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases

A set of 6 base-modified 2′-deoxyadenosine derivatives was incorporated to diverse DNA sequences by primer extension using Vent (exo-) polymerase and the influence of the modification on cleavage by diverse restriction endonucleases was studied. While 8-substituted (Br or methyl) adenine derivatives...

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Detalles Bibliográficos
Autores principales: Macíčková-Cahová, Hana, Hocek, Michal
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794189/
https://www.ncbi.nlm.nih.gov/pubmed/19820117
http://dx.doi.org/10.1093/nar/gkp845

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