Increased functional and structural skin capillary density in type 1 diabetes patients with vascular complications

The present study was designed to study skin capillary density and recruitment of the upper and lower extremities in patients with type 1 diabetes with vascular complications, when compared to patients without complications and healthy subjects. We used intravital video-microscopy to measure basal a...

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Detalles Bibliográficos
Autores principales: Tibiriçá, Eduardo, Rodrigues, Elba, Cobas, Roberta, Gomes, Marilia B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794258/
https://www.ncbi.nlm.nih.gov/pubmed/19958533
http://dx.doi.org/10.1186/1758-5996-1-24
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author Tibiriçá, Eduardo
Rodrigues, Elba
Cobas, Roberta
Gomes, Marilia B
author_facet Tibiriçá, Eduardo
Rodrigues, Elba
Cobas, Roberta
Gomes, Marilia B
author_sort Tibiriçá, Eduardo
collection PubMed
description The present study was designed to study skin capillary density and recruitment of the upper and lower extremities in patients with type 1 diabetes with vascular complications, when compared to patients without complications and healthy subjects. We used intravital video-microscopy to measure basal and maximal (during venous congestion) skin capillary densities as well as capillary recruitment using post-occlusive reactive hyperemia (PORH) in the dorsum of the fingers and toes. Our results showed that besides microvascular vasodilation and loss of autoregulatory capacity, patients with type 1 diabetes with vascular complications present increased skin capillary density in both extremities.
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spelling pubmed-27942582009-12-16 Increased functional and structural skin capillary density in type 1 diabetes patients with vascular complications Tibiriçá, Eduardo Rodrigues, Elba Cobas, Roberta Gomes, Marilia B Diabetol Metab Syndr Short Report The present study was designed to study skin capillary density and recruitment of the upper and lower extremities in patients with type 1 diabetes with vascular complications, when compared to patients without complications and healthy subjects. We used intravital video-microscopy to measure basal and maximal (during venous congestion) skin capillary densities as well as capillary recruitment using post-occlusive reactive hyperemia (PORH) in the dorsum of the fingers and toes. Our results showed that besides microvascular vasodilation and loss of autoregulatory capacity, patients with type 1 diabetes with vascular complications present increased skin capillary density in both extremities. BioMed Central 2009-12-03 /pmc/articles/PMC2794258/ /pubmed/19958533 http://dx.doi.org/10.1186/1758-5996-1-24 Text en Copyright ©2009 Tibiriçá et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Report
Tibiriçá, Eduardo
Rodrigues, Elba
Cobas, Roberta
Gomes, Marilia B
Increased functional and structural skin capillary density in type 1 diabetes patients with vascular complications
title Increased functional and structural skin capillary density in type 1 diabetes patients with vascular complications
title_full Increased functional and structural skin capillary density in type 1 diabetes patients with vascular complications
title_fullStr Increased functional and structural skin capillary density in type 1 diabetes patients with vascular complications
title_full_unstemmed Increased functional and structural skin capillary density in type 1 diabetes patients with vascular complications
title_short Increased functional and structural skin capillary density in type 1 diabetes patients with vascular complications
title_sort increased functional and structural skin capillary density in type 1 diabetes patients with vascular complications
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794258/
https://www.ncbi.nlm.nih.gov/pubmed/19958533
http://dx.doi.org/10.1186/1758-5996-1-24
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