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Amphipathic DNA polymers exhibit antiviral activity against systemic Murine Cytomegalovirus infection

BACKGROUND: Phosphorothioated oligonucleotides (PS-ONs) have a sequence-independent, broad spectrum antiviral activity as amphipathic polymers (APs) and exhibit potent in vitro antiviral activity against a broad spectrum of herpesviruses: HSV-1, HSV-2, HCMV, VZV, EBV, and HHV-6A/B, and in vivo activ...

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Detalles Bibliográficos
Autores principales:	Cardin, Rhonda D, Bravo, Fernando J, Sewell, Andrea P, Cummins, James, Flamand, Louis, Juteau, Jean-Marc, Bernstein, David I, Vaillant, Andrew
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794273/ https://www.ncbi.nlm.nih.gov/pubmed/19954538 http://dx.doi.org/10.1186/1743-422X-6-214

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