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G-protein signaling: back to the future

Heterotrimeric G-proteins are intracellular partners of G-protein-coupled receptors (GPCRs). GPCRs act on inactive Gα·GDP/Gβγ heterotrimers to promote GDP release and GTP binding, resulting in liberation of Gα from Gβγ. Gα·GTP and Gβγ target effectors including adenylyl cyclases, phospholipases and...

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Detalles Bibliográficos
Autores principales:	McCudden, C. R., Hains, M. D., Kimple, R. J., Siderovski, D. P., Willard, F. S.
Formato:	Texto
Lenguaje:	English
Publicado:	Birkhäuser-Verlag 2005
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794341/ https://www.ncbi.nlm.nih.gov/pubmed/15747061 http://dx.doi.org/10.1007/s00018-004-4462-3

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