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Systems toxicology study of doxorubicin on rats using ultra performance liquid chromatography coupled with mass spectrometry based metabolomics

A metabolomics-based systems toxicology approach was used to profile the urinary metabolites for the toxicity related processes and pathogenesis induced by doxorubicin (DOX) to rats. Endogenous metabolite profiles were obtained with ultra performance liquid chromatography-mass spectrometry (UPLC-MS)...

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Detalles Bibliográficos
Autores principales:	Wang, Jiangshan, Reijmers, Theo, Chen, Lijuan, Van Der Heijden, Rob, Wang, Mei, Peng, Shuangqing, Hankemeier, Thomas, Xu, Guowang, Van Der Greef, Jan
Formato:	Texto
Lenguaje:	English
Publicado:	Springer US 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794350/ https://www.ncbi.nlm.nih.gov/pubmed/20046867 http://dx.doi.org/10.1007/s11306-009-0165-3

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