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Diagnosis of biliary tract and ampullary carcinomas
Diagnostic methods for biliary tract carcinoma and the efficacy of these methods are discussed. Neither definite methods for early diagnosis nor specific markers are available in this disease. When this disease is suspected on the basis of clinical symptoms and risk factors, hemato-biochemical exami...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794353/ https://www.ncbi.nlm.nih.gov/pubmed/18274842 http://dx.doi.org/10.1007/s00534-007-1278-6 |
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author | Tsukada, Kazuhiro Takada, Tadahiro Miyazaki, Masaru Miyakawa, Shuichi Nagino, Masato Kondo, Satoshi Furuse, Junji Saito, Hiroya Tsuyuguchi, Toshio Kimura, Fumio Yoshitomi, Hideyuki Nozawa, Satoshi Yoshida, Masahiro Wada, Keita Amano, Hodaka Miura, Fumihiko |
author_facet | Tsukada, Kazuhiro Takada, Tadahiro Miyazaki, Masaru Miyakawa, Shuichi Nagino, Masato Kondo, Satoshi Furuse, Junji Saito, Hiroya Tsuyuguchi, Toshio Kimura, Fumio Yoshitomi, Hideyuki Nozawa, Satoshi Yoshida, Masahiro Wada, Keita Amano, Hodaka Miura, Fumihiko |
author_sort | Tsukada, Kazuhiro |
collection | PubMed |
description | Diagnostic methods for biliary tract carcinoma and the efficacy of these methods are discussed. Neither definite methods for early diagnosis nor specific markers are available in this disease. When this disease is suspected on the basis of clinical symptoms and risk factors, hemato-biochemical examination and abdominal ultrasonography are performed and, where appropriate, enhanced computed tomography (CT) and/or magnetic resonance cholangiopancreatography (MRCP) is carried out. Diagnoses of extrahepatic bile duct cancer and ampullary carcinoma are often made based on the presence of obstructive jaundice. Although rare, abdominal pain and pyrexia, as well as abnormal findings of the hepatobiliary system detected by hemato-biochemical examination, serve as a clue to making a diagnosis of these diseases. On the other hand, the early diagnosis of gallbladder cancer is scarcely possible on the basis of clinical symptoms, so when this cancer is found with the onset of abdominal pain and jaundice, it is already advanced at the time of detection, thus making a cure difficult. When gallbladder cancer is suspected, enhanced CT is carried out. Multidetector computed tomography (MDCT), in particular — one of the methods of enhanced CT — is useful for decision of surgical criteria, because MDCT shows findings such as localization and extension of the tumor, and the presence or absence of remote metastasis. Procedures such as magnetic resonance imaging, endoscopic ultrasonography, bile duct biopsy, and cholangioscopy should be carried out taking into account indications for these procedures in individual patients. However, direct biliary tract imaging is necessary for making a precise diagnosis of the horizontal extension of bile duct cancer. |
format | Text |
id | pubmed-2794353 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Springer-Verlag |
record_format | MEDLINE/PubMed |
spelling | pubmed-27943532009-12-29 Diagnosis of biliary tract and ampullary carcinomas Tsukada, Kazuhiro Takada, Tadahiro Miyazaki, Masaru Miyakawa, Shuichi Nagino, Masato Kondo, Satoshi Furuse, Junji Saito, Hiroya Tsuyuguchi, Toshio Kimura, Fumio Yoshitomi, Hideyuki Nozawa, Satoshi Yoshida, Masahiro Wada, Keita Amano, Hodaka Miura, Fumihiko J Hepatobiliary Pancreat Surg Article Diagnostic methods for biliary tract carcinoma and the efficacy of these methods are discussed. Neither definite methods for early diagnosis nor specific markers are available in this disease. When this disease is suspected on the basis of clinical symptoms and risk factors, hemato-biochemical examination and abdominal ultrasonography are performed and, where appropriate, enhanced computed tomography (CT) and/or magnetic resonance cholangiopancreatography (MRCP) is carried out. Diagnoses of extrahepatic bile duct cancer and ampullary carcinoma are often made based on the presence of obstructive jaundice. Although rare, abdominal pain and pyrexia, as well as abnormal findings of the hepatobiliary system detected by hemato-biochemical examination, serve as a clue to making a diagnosis of these diseases. On the other hand, the early diagnosis of gallbladder cancer is scarcely possible on the basis of clinical symptoms, so when this cancer is found with the onset of abdominal pain and jaundice, it is already advanced at the time of detection, thus making a cure difficult. When gallbladder cancer is suspected, enhanced CT is carried out. Multidetector computed tomography (MDCT), in particular — one of the methods of enhanced CT — is useful for decision of surgical criteria, because MDCT shows findings such as localization and extension of the tumor, and the presence or absence of remote metastasis. Procedures such as magnetic resonance imaging, endoscopic ultrasonography, bile duct biopsy, and cholangioscopy should be carried out taking into account indications for these procedures in individual patients. However, direct biliary tract imaging is necessary for making a precise diagnosis of the horizontal extension of bile duct cancer. Springer-Verlag 2008-02-16 2008-01 /pmc/articles/PMC2794353/ /pubmed/18274842 http://dx.doi.org/10.1007/s00534-007-1278-6 Text en © Springer Japan 2008 |
spellingShingle | Article Tsukada, Kazuhiro Takada, Tadahiro Miyazaki, Masaru Miyakawa, Shuichi Nagino, Masato Kondo, Satoshi Furuse, Junji Saito, Hiroya Tsuyuguchi, Toshio Kimura, Fumio Yoshitomi, Hideyuki Nozawa, Satoshi Yoshida, Masahiro Wada, Keita Amano, Hodaka Miura, Fumihiko Diagnosis of biliary tract and ampullary carcinomas |
title | Diagnosis of biliary tract and ampullary carcinomas |
title_full | Diagnosis of biliary tract and ampullary carcinomas |
title_fullStr | Diagnosis of biliary tract and ampullary carcinomas |
title_full_unstemmed | Diagnosis of biliary tract and ampullary carcinomas |
title_short | Diagnosis of biliary tract and ampullary carcinomas |
title_sort | diagnosis of biliary tract and ampullary carcinomas |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794353/ https://www.ncbi.nlm.nih.gov/pubmed/18274842 http://dx.doi.org/10.1007/s00534-007-1278-6 |
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