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Understanding Gene Sequence Variation in the Context of Transcription Regulation in Yeast
DNA sequence polymorphism in a regulatory protein can have a widespread transcriptional effect. Here we present a computational approach for analyzing modules of genes with a common regulation that are affected by specific DNA polymorphisms. We identify such regulatory-linkage modules by integrating...
Autores principales: | Gat-Viks, Irit, Meller, Renana, Kupiec, Martin, Shamir, Ron |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794365/ https://www.ncbi.nlm.nih.gov/pubmed/20066030 http://dx.doi.org/10.1371/journal.pgen.1000800 |
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