Ultradeep Sequencing of a Human Ultraconserved Region Reveals Somatic and Constitutional Genomic Instability

Early detection of cancer-associated genomic instability is crucial, particularly in tumour types in which this instability represents the essential underlying mechanism of tumourigenesis. Currently used methods require the presence of already established neoplastic cells because they only detect cl...

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Detalles Bibliográficos
Autores principales: De Grassi, Anna, Segala, Cinzia, Iannelli, Fabio, Volorio, Sara, Bertario, Lucio, Radice, Paolo, Bernard, Loris, Ciccarelli, Francesca D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794366/
https://www.ncbi.nlm.nih.gov/pubmed/20052272
http://dx.doi.org/10.1371/journal.pbio.1000275

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