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Neuropeptide Y Knockout Mice Reveal a Central Role of NPY in the Coordination of Bone Mass to Body Weight
Changes in whole body energy levels are closely linked to alterations in body weight and bone mass. Here, we show that hypothalamic signals contribute to the regulation of bone mass in a manner consistent with the central perception of energy status. Mice lacking neuropeptide Y (NPY), a well-known o...
Autores principales: | Baldock, Paul A., Lee, Nicola J., Driessler, Frank, Lin, Shu, Allison, Susan, Stehrer, Bernhard, Lin, En-Ju D., Zhang, Lei, Enriquez, Ronald F., Wong, Iris P. L., McDonald, Michelle M., During, Matthew, Pierroz, Dominique D., Slack, Katy, Shi, Yan C., Yulyaningsih, Ernie, Aljanova, Aygul, Little, David G., Ferrari, Serge L., Sainsbury, Amanda, Eisman, John A., Herzog, Herbert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794533/ https://www.ncbi.nlm.nih.gov/pubmed/20027231 http://dx.doi.org/10.1371/journal.pone.0008415 |
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