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MiR-24 Tumor Suppressor Activity Is Regulated Independent of p53 and through a Target Site Polymorphism
MicroRNAs (miRNAs) are predicted to regulate approximately 30% of all human genes; however, only a few miRNAs have been assigned their targets and specific functions. Here we demonstrate that miR-24, a ubiquitously expressed miRNA, has an anti-proliferative effect independent of p53 function. Cell l...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794546/ https://www.ncbi.nlm.nih.gov/pubmed/20041160 http://dx.doi.org/10.1371/journal.pone.0008445 |