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Real-Time Imaging and Quantification of Amyloid-β Peptide Aggregates by Novel Quantum-Dot Nanoprobes

BACKGROUND: Protein aggregation plays a major role in the pathogenesis of neurodegenerative disorders, such as Alzheimer's disease. However, direct real-time imaging of protein aggregation, including oligomerization and fibrillization, has never been achieved. Here we demonstrate the preparatio...

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Detalles Bibliográficos
Autores principales: Tokuraku, Kiyotaka, Marquardt, Meg, Ikezu, Tsuneya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794548/
https://www.ncbi.nlm.nih.gov/pubmed/20041162
http://dx.doi.org/10.1371/journal.pone.0008492