Domain Motion in Cytochrome P450 Reductase: CONFORMATIONAL EQUILIBRIA REVEALED BY NMR AND SMALL-ANGLE X-RAY SCATTERING

NADPH-cytochrome P450 reductase (CPR), a diflavin reductase, plays a key role in the mammalian P450 mono-oxygenase system. In its crystal structure, the two flavins are close together, positioned for interflavin electron transfer but not for electron transfer to cytochrome P450. A number of lines of...

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Detalles Bibliográficos
Autores principales: Ellis, Jacqueline, Gutierrez, Aldo, Barsukov, Igor L., Huang, Wei-Cheng, Grossmann, J. Günter, Roberts, Gordon C. K.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794777/
https://www.ncbi.nlm.nih.gov/pubmed/19858215
http://dx.doi.org/10.1074/jbc.M109.054304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794777/
https://www.ncbi.nlm.nih.gov/pubmed/19858215
http://dx.doi.org/10.1074/jbc.M109.054304

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