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miRò: a miRNA knowledge base
miRò is a web-based knowledge base that provides users with miRNA–phenotype associations in humans. It integrates data from various online sources, such as databases of miRNAs, ontologies, diseases and targets, into a unified database equipped with an intuitive and flexible query interface and data...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794794/ https://www.ncbi.nlm.nih.gov/pubmed/20157481 http://dx.doi.org/10.1093/database/bap008 |
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author | Laganà, A. Forte, S. Giudice, A. Arena, M. R. Puglisi, P. L. Giugno, R. Pulvirenti, A. Shasha, D. Ferro, A. |
author_facet | Laganà, A. Forte, S. Giudice, A. Arena, M. R. Puglisi, P. L. Giugno, R. Pulvirenti, A. Shasha, D. Ferro, A. |
author_sort | Laganà, A. |
collection | PubMed |
description | miRò is a web-based knowledge base that provides users with miRNA–phenotype associations in humans. It integrates data from various online sources, such as databases of miRNAs, ontologies, diseases and targets, into a unified database equipped with an intuitive and flexible query interface and data mining facilities. The main goal of miRò is the establishment of a knowledge base which allows non-trivial analysis through sophisticated mining techniques and the introduction of a new layer of associations between genes and phenotypes inferred based on miRNAs annotations. Furthermore, a specificity function applied to validated data highlights the most significant associations. The miRò web site is available at: http://ferrolab.dmi.unict.it/miro. Database URL: http://ferrolab.dmi.unict.it/miro |
format | Text |
id | pubmed-2794794 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-27947942009-12-16 miRò: a miRNA knowledge base Laganà, A. Forte, S. Giudice, A. Arena, M. R. Puglisi, P. L. Giugno, R. Pulvirenti, A. Shasha, D. Ferro, A. Database (Oxford) Original Article miRò is a web-based knowledge base that provides users with miRNA–phenotype associations in humans. It integrates data from various online sources, such as databases of miRNAs, ontologies, diseases and targets, into a unified database equipped with an intuitive and flexible query interface and data mining facilities. The main goal of miRò is the establishment of a knowledge base which allows non-trivial analysis through sophisticated mining techniques and the introduction of a new layer of associations between genes and phenotypes inferred based on miRNAs annotations. Furthermore, a specificity function applied to validated data highlights the most significant associations. The miRò web site is available at: http://ferrolab.dmi.unict.it/miro. Database URL: http://ferrolab.dmi.unict.it/miro Oxford University Press 2009 2009-08-04 /pmc/articles/PMC2794794/ /pubmed/20157481 http://dx.doi.org/10.1093/database/bap008 Text en © 2009 The Author(s). http://creativecommons.org/licenses/by-nc/2.0/uk/ This is Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Laganà, A. Forte, S. Giudice, A. Arena, M. R. Puglisi, P. L. Giugno, R. Pulvirenti, A. Shasha, D. Ferro, A. miRò: a miRNA knowledge base |
title | miRò: a miRNA knowledge base |
title_full | miRò: a miRNA knowledge base |
title_fullStr | miRò: a miRNA knowledge base |
title_full_unstemmed | miRò: a miRNA knowledge base |
title_short | miRò: a miRNA knowledge base |
title_sort | mirò: a mirna knowledge base |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794794/ https://www.ncbi.nlm.nih.gov/pubmed/20157481 http://dx.doi.org/10.1093/database/bap008 |
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