Functional membrane androgen receptors in colon tumors trigger pro-apoptotic responses in vitro and reduce drastically tumor incidence in vivo

BACKGROUND: Membrane androgen receptors (mAR) have been implicated in the regulation of cell growth, motility and apoptosis in prostate and breast cancer. Here we analyzed mAR expression and function in colon cancer. RESULTS: Using fluorescent mAR ligands we showed specific membrane staining in colo...

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Detalles Bibliográficos
Autores principales: Gu, Shuchen, Papadopoulou, Natalia, Gehring, Eva-Maria, Nasir, Omaima, Dimas, Konstantinos, Bhavsar, Shefalee K, Föller, Michael, Alevizopoulos, Konstantinos, Lang, Florian, Stournaras, Christos
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794856/
https://www.ncbi.nlm.nih.gov/pubmed/19948074
http://dx.doi.org/10.1186/1476-4598-8-114

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