Retroviral vector integration in post-transplant hematopoiesis in mice conditioned with either submyeloablative or ablative irradiation

X-linked chronic granulomatous disease (X-CGD) is an inherited immunodeficiency with absent phagocyte NADPH oxidase activity caused by defects in the gene encoding gp91(phox). Here we evaluated strategies for less intensive conditioning for gene therapy of genetic blood disorders without selective a...

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Detalles Bibliográficos
Autores principales: Sadat, Mohammed A., Dirscherl, Sara, Sastry, Lakshmi, Dantzer, Jessica, Pech, Nancy, Griffin, Samantha, Hawkins, Troy, Zhao, Yiqiang, Barese, Cecilia N., Cross, Scott, Orazi, Attilio, An, Caroline, Goebel, W. Scott, Yoder, Mervin C., Li, Xiaoman, Grez, Manuel, Cornetta, Kenneth, Mooney, Sean D., Dinauer, Mary C.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795029/
https://www.ncbi.nlm.nih.gov/pubmed/19657370
http://dx.doi.org/10.1038/gt.2009.96

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