Conditional Inactivation of Brca1, p53 and Rb in Mouse Ovaries Results in the Development of Leiomyosarcomas

Epithelial ovarian cancer (EOC) is thought to arise in part from the ovarian surface epithelium (OSE); however, the molecular events underlying this transformation are poorly understood. Germline mutations in the BRCA1 tumor suppressor gene result in a significantly increased risk of developing EOC...

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Detalles Bibliográficos
Autores principales: Clark-Knowles, Katherine V., Senterman, Mary K., Collins, Olga, Vanderhyden, Barbara C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795167/
https://www.ncbi.nlm.nih.gov/pubmed/20046869
http://dx.doi.org/10.1371/journal.pone.0008534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795167/
https://www.ncbi.nlm.nih.gov/pubmed/20046869
http://dx.doi.org/10.1371/journal.pone.0008534

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