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Self-production of tissue factor-coagulation factor VII complex by ovarian cancer cells

BACKGROUND: Thromboembolic events are a major complication in ovarian cancer patients. Tissue factor (TF) is frequently overexpressed in ovarian cancer tissue and correlates with intravascular thrombosis. TF binds to coagulation factor VII (fVII), changing it to its active form, fVIIa. This leads to...

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Detalles Bibliográficos
Autores principales:	Yokota, N, Koizume, S, Miyagi, E, Hirahara, F, Nakamura, Y, Kikuchi, K, Ruf, W, Sakuma, Y, Tsuchiya, E, Miyagi, Y
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795428/ https://www.ncbi.nlm.nih.gov/pubmed/19904262 http://dx.doi.org/10.1038/sj.bjc.6605406

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