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Epac inhibits migration and proliferation of human prostate carcinoma cells

BACKGROUND: It was recently found that cAMP mediates protein kinase A-independent effects through Epac proteins. The aim of this study was to investigate the role of Epac in migration and proliferation of prostate carcinoma cells. METHODS: The effect of Epac activation was determined by [(3)H]thymid...

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Detalles Bibliográficos
Autores principales: Grandoch, M, Rose, A, ter Braak, M, Jendrossek, V, Rübben, H, Fischer, J W, Schmidt, M, Weber, A A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795436/
https://www.ncbi.nlm.nih.gov/pubmed/19920825
http://dx.doi.org/10.1038/sj.bjc.6605439