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Reconstruction of the yeast Snf1 kinase regulatory network reveals its role as a global energy regulator
Highly conserved among eukaryotic cells, the AMP-activated kinase (AMPK) is a central regulator of carbon metabolism. To map the complete network of interactions around AMPK in yeast (Snf1) and to evaluate the role of its regulatory subunit Snf4, we measured global mRNA, protein and metabolite level...
Autores principales: | Usaite, Renata, Jewett, Michael C, Oliveira, Ana Paula, Yates, John R, Olsson, Lisbeth, Nielsen, Jens |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795470/ https://www.ncbi.nlm.nih.gov/pubmed/19888214 http://dx.doi.org/10.1038/msb.2009.67 |
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