Edgetic perturbation models of human inherited disorders

Cellular functions are mediated through complex systems of macromolecules and metabolites linked through biochemical and physical interactions, represented in interactome models as ‘nodes' and ‘edges', respectively. Better understanding of genotype-to-phenotype relationships in human disea...

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Detalles Bibliográficos
Autores principales: Zhong, Quan, Simonis, Nicolas, Li, Qian-Ru, Charloteaux, Benoit, Heuze, Fabien, Klitgord, Niels, Tam, Stanley, Yu, Haiyuan, Venkatesan, Kavitha, Mou, Danny, Swearingen, Venus, Yildirim, Muhammed A, Yan, Han, Dricot, Amélie, Szeto, David, Lin, Chenwei, Hao, Tong, Fan, Changyu, Milstein, Stuart, Dupuy, Denis, Brasseur, Robert, Hill, David E, Cusick, Michael E, Vidal, Marc
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795474/
https://www.ncbi.nlm.nih.gov/pubmed/19888216
http://dx.doi.org/10.1038/msb.2009.80

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