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Network-Free Inference of Knockout Effects in Yeast
Perturbation experiments, in which a certain gene is knocked out and the expression levels of other genes are observed, constitute a fundamental step in uncovering the intricate wiring diagrams in the living cell and elucidating the causal roles of genes in signaling and regulation. Here we present...
Autores principales: | Peleg, Tal, Yosef, Nir, Ruppin, Eytan, Sharan, Roded |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795781/ https://www.ncbi.nlm.nih.gov/pubmed/20066032 http://dx.doi.org/10.1371/journal.pcbi.1000635 |
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